Products

3'-Hydroxyacetophenone(3-HAP)

    Specifications

    HS Code

    648350

    Chemicalformula C8H8O2
    Molarmass 136.15 g/mol
    Physicalstate Solid at room temperature
    Appearance White to off - white powder
    Meltingpoint 58 - 62 °C
    Boilingpoint 296 - 298 °C
    Solubilityinwater Slightly soluble
    Solubilityinorganicsolvents Soluble in ethanol, chloroform, etc.
    Odor Weak, characteristic odor
    Flashpoint 144.4 °C

    As an accredited 3'-Hydroxyacetophenone(3-HAP) factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 3'-Hydroxyacetophenone (3 - HAP) packaged in an air - tight, chemical - resistant container.
    Storage 3'-Hydroxyacetophenone (3 - HAP) should be stored in a cool, dry place, away from heat sources and direct sunlight. Keep it in a well - sealed container to prevent moisture absorption and oxidation. Store it separately from incompatible substances to avoid reactions. It's advisable to maintain storage at a temperature range of around 2 - 8°C if possible for optimal preservation of its chemical properties.
    Shipping 3'-Hydroxyacetophenone (3 - HAP) is shipped with careful packaging in line with chemical safety standards. Usually in sealed containers, safeguarding it from external factors during transit to ensure integrity and safety.
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    3'-Hydroxyacetophenone(3-HAP) 3'-Hydroxyacetophenone(3-HAP) 3'-Hydroxyacetophenone(3-HAP)
    General Information
    Historical Development
    3-Hydroxyacetophenone (3-HAP) is also a product of chemical industry. Its origin was only a matter of academic research at the beginning. In the past, researchers worked hard in the laboratory, trying to understand its properties and its uses.
    At that time, the preparation method was still simple and clumsy, and the yield was meager, which could only be used for basic research. However, with the passage of time and the advancement of science and technology, the preparation process has become more and more exquisite. From the initial crude steps to the fine regulation process, the output has also increased.
    Since its inception, 3-HAP has emerged in various fields. Medicine and fragrances have all seen its shadow. Small used in the past, has now expanded into a multi-domain material. Its development path, just like a prairie fire, from the end of the micro, gradually become a big view of the trend, adding a touch of color to the history of chemical industry.
    Product Overview
    3 '-Hydroxyacetophenone (3-HAP), an organic compound. Its shape or crystalline state, white in color and with a special smell.
    This compound is widely used in the chemical industry. In the synthesis of fragrances, it can be used as an important raw material, giving fragrances a unique flavor. In the field of pharmaceutical chemistry, it also plays a key role as an intermediate for many drug synthesis, helping to create new drugs.
    Its preparation method is mostly through specific chemical reactions to precisely regulate the reaction conditions and achieve higher yield and purity.
    3-HAP is stable in nature, but it is still necessary to follow safety procedures when operating to prevent its potential harm to human body and the environment. Therefore, this compound has significant value and significance in industrial production and scientific research.
    Physical & Chemical Properties
    The physical and chemical properties of 3-hydroxyacetophenone (3-HAP) are quite important in the academic world. Looking at its shape, it is white to light yellow crystalline powder at room temperature, and it smells with a specific fragrance. Its melting point is about 82-84 ° C. Under this temperature, the solids gradually melt and the state changes.
    In terms of solubility, it is easily soluble in organic solvents such as ethanol and ether, but relatively small in water. Its chemical properties are also characteristic. Due to the presence of hydroxyl and carbonyl groups, it can participate in a variety of chemical reactions, such as nucleophilic addition with nucleophiles, or under appropriate conditions, the reaction of hydroxyl groups involved in esterification. Due to its various properties, 3-HAP is widely used in chemical, pharmaceutical, and other fields.
    Technical Specifications & Labeling
    3-Hydroxyacetophenone (3-HAP) is one of the chemical products. Its technical specifications and identification (product parameters) are related to the quality and application of this product. 3-HAP has a unique chemical structure and properties. In the technical specifications, its purity and impurity content are clearly defined. If the purity needs to reach a specific ratio, the type and content of impurities must also be strictly controlled. In terms of identification, product parameters such as name, chemical formula, and dangerous characteristics should be clearly marked. In this way, users can understand its properties and use, ensure that it is used safely, accurately and efficiently in scientific research, production and other activities, and exert its due effect. It can also avoid the risk of misuse due to unknown specifications and labels.
    Preparation Method
    To make 3 '-Hydroxyacetophenone (3-HAP), the method is as follows: First take the required raw materials and study the synthesis process. The raw materials need to be carefully selected to ensure good quality. In the synthesis process, the reaction step is crucial. The first step is to mix the raw materials according to a specific ratio and place them in a suitable reaction vessel. Control the precise temperature and pressure to make the reaction proceed in an orderly manner. This process must be closely monitored to prevent accidents. When the reaction is initially formed, follow the purification process. The way of purification, either by distillation or extraction, depends on the characteristics of the product. After purification, pure 3-HAP can be obtained. The key to its preparation lies in the fine selection of raw materials, accurate reaction, and proper purification. The three complement each other to obtain a good product.
    Chemical Reactions & Modifications
    In recent times, the art of chemistry has become more and more refined, and the research on various compounds has become more and more profound. In today's 3 '-Hydroxyacetophenone (3-HAP), the chemical reaction and modification of this product are quite important in the academic community.
    The preparation of 3-HAP often depends on various reactions. The methods used in the past may be complicated and inefficient. Chemists are exhausted and eager to improve. After years of study, its reaction conditions have gradually been optimized. Such as temperature control and agent selection, the reaction can be more accurate and efficient, and the yield can also be improved.
    And the exploration of its modification has also made considerable progress. After modifying the molecular structure, the characteristics of 3-HAP are changed, and it has more potential for application in materials, medicine and other fields. This is the unremitting exploration of chemists, so that 3-HAP can develop its talents in science and industry, and benefit the world.
    Synonyms & Product Names
    3-Hydroxyacetophenone (3-HAP), the alias and business name of this substance are quite important. Its alias, or those called according to its chemical structure, such as o-hydroxyacetophenone, is named because of the specific position relationship between the hydroxyl group and acetophenone. The trade name is related to commercial circulation. In the market, it may be called by a unique name, hoping to highlight its characteristics and facilitate identification.
    The chemical substances tested are also called to help the academic community communicate and accurately convey their chemical properties. The trade name is a logo in the business, which involves brand perception and market competition. 3-HAP is widely used in the fields of chemical industry, medicine and other fields. The clarity of its alias and trade name is beneficial to all parties in transactions and research. Therefore, exploring the nicknames and business names of 3-HAP is the key to understanding the context of this substance in both academic and commercial circles.
    Safety & Operational Standards
    3 '-Hydroxyacetophenone (3-HAP) Product Safety and Operation Specifications
    3' -Hydroxyacetophenone (3-HAP) is an important thing in chemical research. In order to ensure the safety of experiments and personnel, the following safety and operation specifications should be followed.
    #1. Storage
    3-HAP should be stored in a cool, dry and well ventilated place. Avoid mixing with oxidants, strong acids, strong bases and other substances to prevent violent chemical reactions. The temperature of the storage should be controlled within a specific range, and it should be kept away from fire and heat sources, and must not be exposed to direct sunlight.
    #2. Operation Rules
    When operating, the experimenter must wear suitable protective equipment. Wear protective clothing to prevent 3-HAP from splashing on clothing and causing pollution and corrosion; wear protective gloves, and choose chemical-resistant materials to avoid direct contact with the skin; goggles are also indispensable to protect the eyes from accidental splashing.
    Operating 3-HAP in a fume hood is extremely critical. The fume hood can effectively remove harmful gases generated during operation, reduce the concentration of 3-HAP in the air, and reduce the risk of inhalation by the experimenter.
    When weighing 3-HAP, the action should be precise and gentle to prevent powder from flying. For dissolution or reaction operations, follow the established steps, control the temperature, time and other conditions, and do not change it without authorization.
    #3. Emergency measures
    If you accidentally come into contact with 3-HAP on the skin, rinse quickly with a large amount of flowing water. The rinsing time should be long, and then seek medical treatment. If it splashes into the eye, rinse immediately with a large amount of water, open the eyelids, blink while rushing, and seek medical attention as soon as possible.
    If 3-HAP leaks, cut off the fire source first to avoid the risk of explosion and fire. Small leaks can be absorbed by inert materials such as sand and vermiculite and collected in suitable containers; if a large amount leaks, it needs to be blocked by embankment and transferred to a special collector with an explosion-proof pump for proper disposal.
    Adhering to this safety and operation specification can avoid many risks in 3-HAP operation and ensure the smooth operation of the experiment and the safety of personnel.
    Application Area
    3-Hydroxyacetophenone (3-HAP), in various application fields, great contribution. In the field of medicine, it can be the key raw material for the synthesis of many special drugs, help heal a variety of diseases, and save people's pain. In the field of fragrance, its unique breath can make a wonderful fragrance, increase the charm of fragrance, and attract intoxication. In the field of material science, it can participate in the synthesis of materials, endow materials with special properties, and expand their uses. These 3-HAPs, with their unique properties, play an important role in many application fields such as medicine, fragrance, and materials, and are indeed compounds that cannot be underestimated.
    Research & Development
    Since modern times, chemical refinement, many new things have appeared in the world. Today, 3 - Hydroxyacetophenone (3 - HAP) is a product that we chemical researchers have been focusing on for a long time.
    The properties of 3 - HAP have specific qualities and are available in the fields of chemical industry and medicine. At the beginning, analyzing its structure and exploring its sexual characteristics is the basis for research. Then, think about the method of its system, and strive for efficient and pure production.
    The research path is not smooth, and we encounter many difficulties. The choice of raw materials and the control of reactions all need to be considered. However, we have been unremitting, and after many trials and errors, we have gradually obtained the best method.
    The production of 3-HAP today is purer and more abundant than in the past. In medicine, it can be used to make good medicines; in chemical industry, it can help the production of new materials. In the future, I hope it can shine in a wider area and contribute to the world.
    Toxicity Research
    Wenfu 3 - Hydroxyacetophenone (3 - HAP) has attracted much attention in our chemical research. Its toxicity research is of great significance.
    Looking at past studies to explore the toxicity of 3 - HAP requires careful consideration. After many experiments, it has different effects on organisms. At the microscopic level, it may affect the metabolism of cells and disrupt the normal physiological order. At the macroscopic level, it may inhibit the growth and development of some organisms.
    The study of toxicity is also influenced by many factors. Such as the amount of dose, the length of exposure, and the variety of organisms. Only by studying various factors and understanding their interrelationships can we obtain the true meaning of 3-HAP toxicity, and lay a solid foundation for subsequent use, or to avoid its harm, or to make good use of it, so as to promote the progress of chemical research and protect the safety of ecology and life.
    Future Prospects
    Today, 3 - Hydroxyacetophenone (3 - HAP) has obvious potential in the field of chemical industry. Although it has been used now, there is still a vast space for future expansion.
    In the way of pharmaceutical research and development, it may be used as a precursor. With its structure, it can explore the way of new drug creation, and add powerful wings to the treatment of diseases. In the realm of material science, it is also expected to be modified and optimized to give materials new energy and adapt to diverse needs.
    And if the method of synthesis can be further refined, the yield can be increased, and energy consumption can be reduced, it will definitely be widely used and increase its benefits. Over time, 3-HAP will be able to shine in various fields and become a bright pearl of future chemical development, with endless brilliant prospects.
    Where to Buy 3'-Hydroxyacetophenone(3-HAP) in China?
    As a trusted 3'-Hydroxyacetophenone(3-HAP) manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3'-Hydroxyacetophenone(3-HAP) supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3 -Hydroxyacetophenone (3-HAP)?
    3-Hydroxyacetophenone (3-HAP) has a wide range of uses and is useful in various fields. In the field of medicine, this is a key intermediate. Due to its unique chemical structure and activity, it can participate in the synthesis of many drugs. For example, some drugs with antibacterial and anti-inflammatory effects, 3-HAP can provide the necessary chemical groups in its preparation process to help build pharmaceutical active ingredients and contribute to human healing and health. In the field of fragrances, 3-HAP also plays an important role. It emits a unique aroma and can be prepared with fascinating fragrances. In the manufacture of perfumes, cosmetics and other products, with its aroma characteristics, either as a basic fragrance or as an auxiliary ingredient, it blends with other fragrances to create a fresh and elegant, or rich and charming unique fragrance, satisfying the world's diverse pursuit of aroma. In the field of organic synthesis, 3-HAP is an indispensable raw material. Due to the existence of its activity check point, chemists can modify and expand its structure through various chemical reactions. Synthesize organic compounds with more complex structures and more diverse functions. These compounds may emerge in the field of materials science or serve as new catalysts to promote the continuous development of organic synthetic chemistry and expand the boundaries of human understanding and application of organic substances.
    What are the physical properties of 3 -Hydroxyacetophenone (3-HAP)?
    3-Hydroxyacetophenone (3-HAP) is one of the organic compounds with special physical properties, which is described in detail today. First of all, its appearance, under room temperature and pressure, 3-HAP is mostly white to light yellow crystalline powder state, delicate and uniform, and the appearance is quite textured. This form is easy to store and use, and it is convenient in many experimental and industrial processes. Second describes its melting point, about 79-82 ° C. Melting point is an important physical property of a substance. This specific melting point value not only helps to identify 3-HAP, but also is crucial to control the temperature to achieve its phase transition in the relevant production process. For example, in the purification process, according to the melting point characteristics, precise temperature control can be used to separate impurities to obtain pure 3-HAP. Furthermore, 3-HAP is slightly soluble in water. Water is a common solvent, and this solubility indicates that in order to disperse 3-HAP in water, special means are required, such as adding appropriate surfactants. However, it is soluble in organic solvents such as ethanol and ether. Organic solvents such as ethanol and ether have unique molecular structures and are compatible with the intermolecular forces of 3-HAP molecules, so they can be miscible. This solubility provides a broad space for their application in organic synthesis, drug preparation and other fields. For example, in drug research and development, 3-HAP can be dissolved in organic solvents, and then uniformly mixed with other drug ingredients to improve the efficacy. In addition, 3-HAP has a certain degree of volatility. Although the volatility is not strong, it will evaporate slowly in an open system and in a higher temperature environment. This characteristic reminds that when storing and using, proper sealing and temperature control measures should be taken to avoid its volatilization loss and ensure its quality and efficacy. In summary, the physical properties of 3-HAP, such as appearance, melting point, solubility, volatility, etc., have their own uses, and play a pivotal role in the research and production of chemical, pharmaceutical and other fields.
    What are the chemical synthesis methods of 3 '-Hydroxyacetophenone (3-HAP)
    The chemical synthesis method of 3-hydroxyacetophenone (3-HAP) is described in detail by you today. First, the method of using m-hydroxyphenylacetonitrile as the raw material. By co-heating m-hydroxyphenylacetonitrile with acid and hydrolyzing, 3-hydroxyacetophenone can be obtained. This reaction requires attention to the control of reaction temperature and time. If the temperature is too high or the time is too long, it may cause the product to decompose or form by-products. Second, the method of using m-methoxyacetophenone as the raw material. First, m-methoxyacetophenone is combined with reagents such as hydroiodic acid or boron tribromide to remove the methoxyl group to obtain 3-hydroxyacetophenone. However, hydroiodic acid is highly corrosive, and boron tribromide is also active. It is necessary to be careful during operation, use good ventilation, and take complete protective measures. Third, acetophenone is used as raw material and is acylated by Fu-g. Using Lewis acids such as aluminum trichloride as catalysts, acetophenone is reacted with acetyl chloride or acetic anhydride to obtain meta-substituted 3-hydroxyacetophenone. However, the selectivity of this reaction is not good, and it is often accompanied by ortho-and para-substituted by-products. The reaction conditions need to be carefully optimized, such as adjusting the amount of catalyst, reaction temperature and solvent type, in order to improve the yield and selectivity of the target product. There are many methods for synthesizing 3-hydroxyacetophenone, each with advantages and disadvantages. In practical application, the appropriate synthesis path should be carefully selected according to various factors such as raw material availability, cost, yield and purity.
    What is the price range of 3 -Hydroxyacetophenone (3-HAP) in the market?
    I have not heard of the exact price of 3-hydroxyacetophenone (3-HAP) on the market. The price of this drug often varies with many factors, and it is difficult to hide it in one word. First, it is related to the price of raw materials. If the raw materials required for its production are expensive and rare, the price of 3-HAP is also high; conversely, if the raw materials are easily available and cheap, the price may drop. Second, it depends on the simplicity of the process. If the production requires exquisite and complicated methods, labor is expensive and time-consuming, and the cost increases, the price will also follow; if the process is simple, the cost will decrease and the price will also decrease. Third, the state of market supply and demand has a great impact. If there are many people who want it and there are few people who supply it, the price will rise; if the supply exceeds the demand, the price may fall. Fourth, the place of production and the enterprise are also related to the price. Different places have different taxes and labor costs; different enterprises have different scales and management methods, resulting in poor prices. However, if you want to know the approximate market price, you can visit the chemical raw material trading platform, related industry websites, or consult chemical product suppliers. There may be a newer and accurate price range to show the current market price of this drug.
    What are the storage conditions for 3 -Hydroxyacetophenone (3-HAP)?
    3-Hydroxyacetophenone (3-HAP) is an organic compound. It should be stored in a cool and dry place, away from direct sunlight. Sunlight is a source of heat and energy, but 3-HAP is harmful. Under direct exposure, it may cause it to decompose and deteriorate, damage its chemical properties, and lose its original quality. Furthermore, the storage place must be well ventilated. Air circulation can dissipate volatile gases that may accumulate. If it is in a closed place, the volatile gas will gradually accumulate, which will increase the risk of fire, and may cause chemical reactions with other substances, endangering the existence of 3-HAP. Repeated, it should be stored separately with oxidants, acids, bases and other substances. These substances have strong chemical activity and coexist with 3-HAP, which is easy to react violently. Such as oxidizing agents, which have strong oxidizing properties, or oxidize 3-HAP, causing structural changes and properties to change; acids and bases can also interact with certain groups in 3-HAP, resulting in impure compositions and reduced quality. Also, storage devices are also exquisite. A sealed container should be used, preferably glass or specific plastic materials. Glass is chemically stable and is not easy to interact with 3-HAP; specific plastics can resist its corrosion, and the sealing effect can prevent volatilization and the invasion of external impurities. In short, if you want to store 3-HAP well, you must follow the rules of cool, dry, well-ventilated, classified storage, and suitable containers, so as to ensure its quality for later use.