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What are the main uses of dihexyl adipate (DHA)?
Diethyl adipate (DHA) has a wide range of uses.
One of them is often an important raw material in chemical synthesis. It can participate in a variety of organic synthesis reactions, and through exquisite processes, it can breed many compounds with special properties. Taking the ester exchange reaction as an example, it interacts with different alcohols to form esters with different structures, which are widely used in fragrances, coatings and many other fields. In the preparation of fragrances, the newly formed esters can give the fragrances a unique aroma, providing more abundant materials for perfumers to prepare thousands of flavors of fragrances to meet the diverse needs of the world for aroma.
Second, in the field of medicine, it also has extraordinary achievements. In the process of pharmaceutical preparations, it can be used as a solvent. Because of its good solubility, it can help the active ingredients of the drug to be evenly dispersed, improving the stability and bioavailability of the drug. And its chemical properties are relatively mild, less irritating to the human body, so it is favored by pharmaceutical manufacturers in the process of drug development and production. It can be seen in many oral preparations or injections, paving the way for the smooth development of drug efficacy.
Third, it also plays a key role in the field of plastic additives. It can be used as a plasticizer and added to plastics, which can significantly improve the flexibility and processing properties of plastics. Plasticized plastic products, such as common polyvinyl chloride (PVC) products, are not easy to crack, can adapt to more complex use environments, and are widely used in packaging, building materials and many other industries. Make packaging materials more flexible and durable, and building materials products more practical and aesthetic.
Fourth, in the coating industry, it is also indispensable as a solvent and film-forming aid. As a solvent, it can fully mix the ingredients in the coating to ensure the uniformity of the coating; and as a film-forming aid, it can help the coating form a continuous and dense coating film, improving the gloss, hardness and wear resistance of the coating. Whether it is architectural coatings used to protect and decorate buildings, or industrial coatings used to protect machinery and equipment, diethyl adipate plays an important role and contributes significantly to the optimization of coating performance.
What are the chemical properties of dihexyl adipate (DHA)?
Diethyl adipate (DHA) is an organic compound. It has many chemical properties, which are described below.
First, it has the general properties of esters. Due to the ester group, hydrolysis can occur. Under acidic conditions, hydrolysis produces adipic acid and ethanol, which is a reversible process. If sulfuric acid is used as a catalyst, diethyl adipate gradually dissolves into adipic acid and ethanol when heated. The chemical equation for hydrolysis is: $C_ {10} H_ {18} O_ {4} + H_ {2} O\ stackrel {H ^{+}}{\ rightleft harpoons} C_ {6} H_ {10} {4} + 2C_ {2} H_ {5} OH $. Under basic conditions, the hydrolysis is more thorough, resulting in the formation of adipate and ethanol, and this reaction is irreversible. Taking sodium hydroxide solution as an example, diethyl adipate rapidly interacts with sodium hydroxide to form sodium adipate and ethanol. The chemical equation is: $C_ {10} H_ {18} O_ {4} + 2NaOH\ rightarrow C_ {6} H_ {10} O_ {4} Na_ {2} + 2C_ {2} H_ {5} OH $.
Second, the alcoholysis reaction can be carried out. Under the action of catalyst, the ethoxy group of diethyl adipate can be replaced by the alkoxy group of other alcohols to form new esters and ethanol. For example, with methanol catalyzed by sulfuric acid, dimethyl adipate can be obtained with ethanol. The reaction equation is: $C_ {10} H_ {18} O_ {4} + 2CH_ {3} OH\ stackrel {H_ {2} SO_ {4}} {\ rightleftharpoons} C_ {8} H_ {14} O_ {4} + 2C_ {2} H_ {5} OH $.
Third, it can participate in the aminolysis reaction. When interacting with ammonia, the ethoxy group of the ester group is replaced by the amino group to form adipamide and ethanol. This reaction usually needs to be carried out under heating and appropriate catalyst conditions. The chemical equation is: $C_ {10} H_ {18} O_ {4} + 2NH_ {3}\ stackrel {\ Delta} {\ rightarrow} C_ {6} H_ {12} N_ {2} O_ {2} + 2C_ {2} H_ {5} OH $.
Fourth, due to the presence of methylene in the molecule, the substitution reaction of α-hydrogen can occur under certain conditions. If there is light or an initiator, it can be replaced with halogen elements, and the hydrogen on the methylene is replaced by halogen atoms. Taking bromine as an example, under light, the methylene hydrogen in diethyl adipate can be gradually replaced by bromine atoms to form bromine-containing substitutes.
Fifth, it is flammable. As an organic compound, it can be completely burned when oxygen is sufficient to generate carbon dioxide and water. The chemical equation for combustion is: $C_ {10} H_ {18} O_ {4} + 13O_ {2}\ stackrel {ignited }{=\!=\!=} 10CO_ {2} + 9H_ {2} O $.
What are the precautions for dihexyl adipate (DHA) in the production process?
For docosahexaenoic acid (DHA), many matters should be paid attention to during the production process.
Selection of the first raw material. The source of the raw material is related to the quality of the product. It is advisable to choose a pure and pollution-free source, such as marine microalgae or deep-sea fish. DHA produced by marine microalgae is relatively pure and less susceptible to heavy metal pollution such as mercury; although deep-sea fish are rich in DHA, it may contain pollutants. Therefore, when selecting materials, it is important to carefully observe the environment of the place of origin to ensure the safety and reliability of the raw materials.
Times and production process. The extraction process should be exquisite. If the extraction method is used, the appropriate extractant should be selected, and the temperature, time and other conditions can be precisely controlled to extract efficiently and maintain its activity. Or fermentation method, adjust the strain, medium composition and fermentation environment, such as temperature, pH value, so that the strain can produce DHA. When refining, remove impurities, maintain purity, and obtain high-purity DHA by chromatography, crystallization and other techniques.
Furthermore, the production environment is also the key. The plant must be clean, meet the corresponding hygiene standards, and avoid microbial contamination. The equipment is often maintained, clean, and stable in operation. Failure-proof product quality problems. Personnel operate according to specifications, have been professionally trained, and are familiar with the production process and quality control points.
And storage and transportation should not be ignored. DHA is easy to oxidize, and should be stored at low temperature, protected from light, and oxygen barrier. It should be sealed and packaged with antioxidants. During transportation, keep the appropriate temperature and humidity to avoid quality deterioration caused by bumps and high temperatures.
All of these, in the whole process of docosahexaenoic acid production, careful attention can be paid to produce high-quality products, suitable for all parties.
What are the advantages of dihexyl adipate (DHA) over other similar products?
Docosahexaenoic acid (DHA) has outstanding advantages among similar products.
The first is its function in brain and visual development. Brain, the cardinal of the human body, and DHA is an important component of brain cell membranes, which can help nerve conduction, make thinking agile, and cognitive refinement. If children are fully nourished by DHA during development, wisdom will be developed early and learning will be easy. As for vision, the retina in the eye is also rich in this substance, which can optimize the function of visual cells, make vision clear, and has significant visual ability. Compared with other products, it is more effective in promoting brain and visual development.
Furthermore, in terms of cardiovascular, DHA can adjust blood lipids and make blood flow smoothly. It can reduce the amount of triglycerides, reduce the viscosity of the blood, prevent the formation of thrombosis, and maintain the transparency of blood vessels. It is like river dredging, and the boat is unimpeded. Compared with other cardiovascular products, DHA has a mild and comprehensive effect, and does not have many disadvantages.
And DHA also has special effects in anti-inflammatory aspects. It can regulate the body's inflammatory response and make the internal environment peaceful. If inflammation is blazing, various diseases are prone to occur. DHA can slow it down, just like spring rain moisturizing the body, quietly calming the trend of inflammation, which is not easily comparable to other products.
And it is also beneficial to immune regulation. It can relax the immune system to a certain extent, and when it resists external evil, it will not be too hyperactive and self-injure. When it is weak, it can vibrate its strength, which is more stable and orderly than other immune-regulating products.
It is based on this. Compared with other similar products, docosahexaenoic acid (DHA) has full advantages in brain and visual development, cardiovascular maintenance, anti-inflammatory and immune regulation, etc. It is actually a good product for health care.
What is the market price range for dihexyl adipate (DHA)?
At present, the price range of DHA (that is, docosahexaenoic acid) in the market varies depending on the category, source and quality.
At the end of the category, if it is the DHA mentioned in fish oil, the price varies depending on the variety and origin of the fish. Common, in the market, the price per gram may be between a few cents and a few yuan. Cover fish oil comes from a wide range of sources, but the quality varies. Different fishing places have different nutrient compositions of fish, so the price fluctuates.
If it is the DHA mentioned in algal oil, the price varies depending on the extraction process and algae species. Algae oil DHA is often derived from artificially cultivated algae, and the quality is relatively stable. Its price per gram, or a few yuan to more than ten yuan. Because of its controllable cultivation and few impurities, it is preferred by those who seek high quality, so the price is slightly higher.
Looking at the quality again, DHA with high purity is expensive. If the purity reaches more than 90%, regardless of the source of fish oil or algal oil, the price per gram can reach tens of yuan. Because of its difficulty in extraction, it requires a fine process, which is expensive, so the price is high. For ordinary purity, the price is close to the people, mostly in a few yuan per gram.
There is also a source influence. The price of natural deep-sea fish oil is high due to the precious deep-sea resources, coupled with the cost of fishing and transportation. The cost of artificially cultivating algae is controllable, but the process is also high and low, and the price is also different.
In summary, the market price of DHA can range from a few cents per gram to a few tens of yuan per gram. Buyers should choose according to their own needs and quality.