Products

4’-Hydroxyacetophenone

    Specifications

    HS Code

    773224

    Name 4'-Hydroxyacetophenone
    Molecular Formula C8H8O2
    Molar Mass 136.15 g/mol
    Appearance White to off - white crystalline powder
    Odor Faint sweet odor
    Melting Point 109 - 111 °C
    Boiling Point 296.5 °C
    Solubility Slightly soluble in water, soluble in ethanol, ether, chloroform
    Density 1.25 g/cm³ (at 20 °C)
    Flash Point 141.6 °C
    Cas Number 99 - 93 - 4

    As an accredited 4’-Hydroxyacetophenone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4’ -Hydroxyacetophenone packaged in resealable plastic bags.
    Storage 4′ -Hydroxyacetophenone should be stored in a cool, dry place away from heat sources, open flames, and incompatible substances. Keep it in a tightly - closed container to prevent moisture and air exposure, as it may react with these elements. Store it separately from oxidizing agents to avoid potential reactions that could compromise its quality.
    Shipping 4’-Hydroxyacetophenone is typically shipped in well - sealed containers to prevent exposure. Care is taken due to its chemical nature, ensuring proper insulation and secure packaging to avoid any damage during transit.
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    4’-Hydroxyacetophenone 4’-Hydroxyacetophenone 4’-Hydroxyacetophenone
    General Information
    Historical Development
    4 '-Hydroxyacetophenone, it is also an important product of chemistry. Its origin is early, the first time, and it has been observed many times in the research and development of chemistry. In the early days, the research is still in progress, and its one or two characteristics are known.
    And the development of the technology in the future, the investigation of the 4' -Hydroxyacetophenone is deeper. People have studied the mystery of its molecules, and further studied its properties. Under different environments and conditions, the results of the study are different, and the purpose of the researcher is known.
    As for the use, initial or limited, and the research and promotion of it, it is still in many fields such as medicine, fragrance, etc., and its skills are developed and its effectiveness is increasing. Therefore, the 4 '-Hydroxyacetophenone from the beginning of the beginning, the month, the research is not good, and the use is also wide, the future scene, the expected more.
    Product Overview
    4 '-Hydroxyacetophenone, the organic compound is also. Its color is often white to light yellow crystalline, with a unique fragrant smell. This compound has a wide range of uses in the chemical industry. In the synthesis of medicine, it can be a key intermediate to help the preparation of a variety of drugs, such as the synthesis of some analgesic and anti-inflammatory drugs. In the fragrance industry, its unique aroma is also used, which can add a unique flavor to the fragrance formula.
    Its preparation method is often achieved by a specific chemical reaction. The raw materials are carefully proportioned and under suitable reaction conditions, such as specific temperature, pressure and catalyst, undergo chemical transformation, and finally 4' -Hydroxyacetophenone. Its chemical properties are relatively stable, but in a specific chemical environment, it can also exhibit active reactivity and participate in various organic reactions, thus playing an important role in the field of organic synthesis.
    Physical & Chemical Properties
    4 '-Hydroxyacetophenone, organic compounds are also. It has specific physical and chemical properties. Looking at its physical properties, at room temperature, it is a white to light yellow crystalline solid with a faint aromatic smell. The melting point is about 108-110 degrees Celsius. This characteristic makes it appear different physical forms in a specific temperature environment.
    On its chemical properties, because it contains hydroxyl and carbonyl groups, it has certain reactivity. Hydroxyl groups can participate in esterification, etherification and other reactions, while carbonyl groups can undergo nucleophilic addition. It can react with many reagents and is widely used in the field of organic synthesis. With such physical and chemical properties, 4' -Hydroxyacetophenone can be used in medicine, fragrance and other industries, and is an important raw material for many industries.
    Technical Specifications & Labeling
    4 '-Hydroxyacetophenone are organic compounds, which need to be prepared according to specific technical specifications and standards. In terms of technical specifications, the reaction conditions are extremely critical. Usually phenol and acetyl chloride are used as raw materials, and the acylation reaction is carried out under the catalysis of anhydrous aluminum trichloride. The reaction temperature should be controlled at a low temperature, about 0-5 ° C, to prevent side reactions from occurring. The reaction time needs to be precisely controlled according to the proportion of raw materials and the reaction process, usually several hours.
    In terms of product standards, the appearance should be white to light yellow crystalline powder, which can be visually distinguished. The purity needs to be above 98%, which can be accurately determined by high performance liquid chromatography (HPLC). The melting point range is 108-111 ° C, and it is accurately measured by a melting point meter. The impurity content must be strictly controlled, and each impurity must not exceed the specified limit to ensure stable product quality and meet the needs of different application scenarios.
    Preparation Method
    4 '-Hydroxyacetophenone is an important organic compound, and its preparation method is quite critical. In the selection of raw materials, phenol and acetyl chloride are often used as the starting materials. In the preparation process, phenol is first dissolved in an appropriate organic solvent, and acetyl chloride is slowly added dropwise in a low temperature environment. This is the initial step of the reaction.
    During the reaction process, it is necessary to strictly control the temperature and reaction time. Generally speaking, the temperature should be controlled at 0-5 ° C. After the dropwise addition is completed, gradually heat up to room temperature and continue to stir the reaction for several hours. After the reaction is completed, the product is separated and purified by suitable post-treatment methods such as extraction, distillation, and recrystallization.
    In terms of catalytic mechanism, Lewis acid is often used as a catalyst, such as anhydrous aluminum trichloride. It can effectively promote the reaction between phenol and acetyl chloride, reduce the activation energy of the reaction, and thereby improve the reaction rate and yield. In this way, through rational selection of raw materials, precise control of reaction steps and appropriate catalytic mechanisms, efficient preparation of 4 '-Hydroxyacetophenone can be achieved.
    Chemical Reactions & Modifications
    4 '-Hydroxyacetophenone, organic compounds are also. The chemical reaction and modification of this compound are the gist of our research.
    In the past, this compound was prepared by traditional methods, but its yield was not ideal and the reaction conditions were harsh. In order to improve, we investigated various reaction paths in detail.
    After exploration, it was found that the reaction of phenols and acetylating reagents can modify it. Changing the temperature of the reaction, solvent, or adding a specific catalyst can adjust the rate of the reaction and the purity of the product.
    If the temperature is appropriately increased, the reaction rate will be accelerated, but if it is too high, side reactions will breed. Choosing the right solvent can increase the solubility of the reactants and promote the reaction. The application of the new catalyst can also significantly improve the quality and yield of the product, opening up new avenues for the production improvement of 4 '-Hydroxyacetophenone.
    Synonyms & Product Names
    4 '-Hydroxyacetophenone, it is also a chemical substance. The same name is the name of the product, and there is no way to investigate it.
    4' -Hydroxyacetophenone, there is also acetophenone. This name is based on its transformation, "" indicates the relative position of its substituent; "" indicates that it contains -OH group; "acetophenone" indicates the combination of its benzene and acetophenone.
    Its trade name is also different in the market. Or it is named because of its characteristics and uses. It has the effect of anti-corrosion and anti-corrosion, and for the quality of chemical products, merchants use specific trade names to recognize its efficacy and attract the purpose of those who eliminate it. However, it is all 4 '-Hydroxyacetophenone this thing. The complexity of the same name and commodity name is the importance of the use of this thing and the importance of the work.
    Safety & Operational Standards
    4 '-Hydroxyacetophenone safety and handling practices
    4' -Hydroxyacetophenone are common compounds in chemical preparation and research. Safety regulations are of paramount importance during its experimental operation and use.
    First word safety protection. Experimenters must wear appropriate laboratory clothes, which are the first barrier against potential chemical spills and contamination. And protective gloves must be worn. When choosing gloves, their tolerance to 4 '-Hydroxyacetophenone must be considered to prevent penetration. Face protection is also indispensable. Goggles or masks can effectively protect the eyes from accidental spills.
    Furthermore, the operating environment. Experiments should be carried out in a well-ventilated place, preferably in a fume hood. Due to the 4 '-Hydroxyacetophenone or volatilization of harmful gases, good ventilation can be discharged in time to reduce the concentration in the air and protect the safety of the experimenter's breathing.
    Operating specifications should not be ignored. When taking 4' -Hydroxyacetophenone, the action should be stable and accurate to prevent substances from spilling. If it is a solid, scoop it carefully with a clean spoon; if it is a liquid, measure it with a suitable pipette. During the weighing process, accurately operate the balance to ensure that the dosage is correct.
    After the experiment is completed, properly dispose of the remaining 4 '-Hydroxyacetophenone and related waste. Do not dump at will, should be in accordance with chemical waste disposal regulations, classified storage, for professional disposal, so as not to pollute the environment.
    If you accidentally come into contact with the 4 '-Hydroxyacetophenone and touch the skin, rinse with a lot of water quickly, and then seek medical attention according to the situation; if you enter the eyes, rinse with a lot of water immediately, and seek medical attention as soon as possible.
    By abiding by this safety and operation specification, you can ensure the smooth research and use of the 4' -Hydroxyacetophenone, protect the safety of the experimenter, and avoid environmental harm.
    Application Area
    4 '-Hydroxyacetophenone, this substance has a wide range of application fields. In the field of medicine, it is a key raw material for many drug synthesis, helping to develop drugs for the treatment of various diseases, which can improve the efficacy and optimize the pharmacological properties. In the fragrance industry, because of its unique chemical structure, it can endow fragrances with a different aroma, which is commonly used for the preparation of unique fragrances. In the field of chemical materials, it can participate in the synthesis of high-performance materials to enhance material stability, durability and other properties. And it has a significant position in the field of organic synthesis. As an important intermediate, it can derive many organic compounds with specific functions, providing basic support for the development of many industries, and promoting technological innovation and product optimization in various fields.
    Research & Development
    Modern chemistry has advanced, and it has been deeply studied in various compounds. 4 '-Hydroxyacetophenone This substance has gradually become the focus of our generation of chemical researchers.
    The beginning of its research is due to the observation of its unique structure or extraordinary properties. At the beginning, only its basic composition was known, and many tests were required to explore its details. We set up various experiments to observe its reaction state with other substances and measure its physical properties. After going through cold and heat, we can understand its reaction law under specific conditions.
    As for development, the prospect is quite good. In the field of medicine, it may become new pharmaceutical raw materials to help heal patients; in terms of materials, it may be able to add new materials and increase their functions. Although the road ahead is long, we chemical researchers must use our perseverance to eliminate its mysteries and promote its development, making it useful to the world.
    Toxicity Research
    4 '-Hydroxyacetophenone, it is also a chemical thing. We use chemical research, especially in the study of its toxicity. This compound has been studied in the laboratory to reveal the impact of its toxicity.
    All kinds of research to observe the effects of different organisms. For some microorganisms, it can be inhibited to a certain extent, or it can be replaced by other organisms. And in the cells of higher organisms, it also affects its activity.
    However, toxicity research is not done overnight, and it needs to be done many times to consider the different degrees and effects. In order to clarify its toxicity, so that it can be used in terms of industrial use, environmental impact and biological safety, so that this substance can be used for its own purposes and avoid its harm.
    Future Prospects
    Today there is a name 4 '-Hydroxyacetophenone. In the field of my chemical research, its future prospects are worth exploring. This substance has unique chemical properties and has unlimited potential in the fields of medicine and materials.
    Looking at medicine, it may be possible to use its characteristics to develop new drugs, cure various diseases, and seek well-being for the common people. As for the field of materials, it is expected to improve performance, create novel materials, and meet the needs of future technology.
    Our chemical researchers should study diligently, explore its properties, and explore the boundaries of application. With unremitting efforts, we hope to make 4' -Hydroxyacetophenone shine in the future, contribute to the progress of the world, and paint a brilliant new chapter.
    Where to Buy 4’-Hydroxyacetophenone in China?
    As a trusted 4’-Hydroxyacetophenone manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4’-Hydroxyacetophenone supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of -Hydroxyacetophenone?
    4-Hydroxyacetophenone (4-Hydroxyacetophenone) is widely used and has important functions in many fields. In the field of medicine, this is the key intermediate of traditional Chinese medicine. The synthesis of many drugs requires it as the starting material, and through a series of chemical reactions, it is converted into compounds with more complex structures and specific pharmacological activities. For example, some antipyretic and analgesic drugs, 4-Hydroxyacetophenone can be modified and derived to construct molecular structures with ideal pharmacokinetic properties, and then exert the efficacy of treating diseases. In the fragrance industry, it also occupies a place. Because of its own unique aroma, it can prepare many types of fragrances. It can impart a special flavor to the fragrance, making its aroma richer and more distinct. When blending a variety of fragrances such as floral and fruity, an appropriate amount of 4-hydroxyacetophenone can be added to optimize the aroma quality and add a unique flavor. It is widely used in daily chemicals such as perfumes, skin care products, detergents and other products to enhance the aroma attractiveness of the product. In the field of organic synthesis, 4-hydroxyacetophenone, as an important building block for organic synthesis, can participate in a variety of organic reactions. For example, through nucleophilic substitution and condensation reactions with different reagents, other functionalized organic compounds can be prepared, providing a rich selection of raw materials for the research and development of organic synthetic chemistry, promoting the continuous progress of organic synthetic chemistry, and assisting in the synthesis of more organic materials with novel structures and unique properties.
    What are the physical properties of -Hydroxyacetophenone?
    4-Hydroxyacetophenone, its physical properties are as follows: This substance is white to light yellow crystalline powder at room temperature, and it looks fine. Smell it, it has a weak and special smell. Its melting point is between 108-110 ° C. When heated to this temperature range, it gradually changes from solid to liquid. The boiling point is about 296.4 ° C. When heated to this temperature, it turns into a gaseous state. 4-Hydroxyacetophenone is slightly soluble in cold water, but in hot water, the solubility is slightly increased, and it is quite easy to dissolve in organic solvents such as ethanol and ether. This is due to the characteristics of its molecular structure, which is different from the forces between different solvent molecules. Its density is about 1.131g/cm ³, which is slightly heavier than water. The appearance is pure, the color is uniform, and the crystalline form is regular. Because of its physical properties, it is used in many fields. In the field of medicine, because of its specific physical and chemical properties, it can be used as a raw material for synthetic drugs; in the fragrance industry, with its weak smell, it can participate in the formulation of unique aromas. Understanding the physical properties of 4-hydroxyacetophenone is of great significance in grasping its characteristics and expanding the scope of application.
    What are the applications of -Hydroxyacetophenone in synthesis?
    4-Hydroxyacetophenone has many uses in the synthesis of various things. In the field of pharmaceutical synthesis, it can be used as a key raw material and participates in the creation of many drugs. For example, some antipyretic and analgesic agents, starting with 4-hydroxyacetophenone, through serial transformation, can obtain drugs with curative effects. Due to its structural characteristics, specific groups can be introduced to give drugs the required pharmacological activity. It is also indispensable in the synthesis of fragrances. It has unique aroma characteristics and can add a different flavor to fragrances. It can be chemically modified to adjust the intensity and tonality of aroma to produce fragrances suitable for different scenes, either rich or elegant, which are useful in daily chemical perfumes, skin care products, etc. Furthermore, in the study of organic synthesis chemistry, 4-hydroxyacetophenone is often used as an important intermediate. Due to the activity of phenolic hydroxyl and carbonyl groups, it can participate in various reactions, such as esterification and condensation. With these reactions, chemists can construct complex organic molecules, expand the boundaries of organic synthesis, and pave the way for the development of new materials and new drugs. In the field of materials science, 4-hydroxyacetophenone also has potential applications. Or it can be introduced into polymer materials through specific reactions to improve material properties, such as enhancing thermal stability and enhancing mechanical properties, providing a new way for the creation of new materials.
    What are the storage conditions for 4 '-Hydroxyacetophenone?
    4-Hydroxyacetophenone is one of the organic compounds. The most important thing for its storage is to place it in a cool, dry and well-ventilated place. Because of the cool place, it can avoid the change of its properties caused by high temperature. In a dry environment, it can prevent the intrusion of moisture and prevent it from being damp and bad. With good ventilation, harmful gases can be dispersed in time to maintain their quality. Furthermore, it must be kept away from fires and heat sources. Fire and heat can easily cause it to explode, causing danger. This compound is flammable, and it is very likely to burn in case of open flames and hot topics, so preventing fires is the key to storage. And it should be placed separately from oxidizing agents and cannot be mixed. The oxidizing agent has strong oxidizing properties. When it encounters 4-hydroxyacetophenone, it may cause a violent chemical reaction, which endangers safety. The storage place should be equipped with suitable materials to contain the leakage. To prevent accidental leakage, it can be properly handled in time to prevent its diffusion and minimize harm. The package must also be sealed to prevent water vapor, air, etc. from contacting its contents to ensure the stability of its chemical properties. In this way, it is the way to properly store 4-hydroxyacetophenone.
    What is the market price of 4 '-Hydroxyacetophenone?
    In today's world, business conditions are treacherous and the market is impermanent. It is difficult to judge the market price of 4% 27 - Hydroxyacetophenone. The price of this chemical substance is influenced by various factors. First, the price of raw materials, if the price of all raw materials required for its production rises and falls, the price of 4% 27 - Hydroxyacetophenone will also fluctuate. If the raw materials are rare and difficult to obtain, the manufacturing cost will be high, and the price will be very high; on the contrary, if the raw materials are abundant and cheap, the price may be slightly reduced. Second, the supply and demand trend is crucial. If there is a strong demand for this product in the city, but the output is limited and the supply is in short supply, the price will rise; if the demand is sluggish, the output is excessive, the supply exceeds the demand, and the price will decline. Third, the progress of the process also has an impact. As soon as the new technique is released, if it can make the production convenient and the cost is reduced, the price may change accordingly. Or because of the improvement of quality, it is important for the market, and the price may also be different. Fourth, decrees and regulations must not be ignored. Tax increases or decreases, and changes in environmental protection regulations can all make costs different, which in turn affects the market price. If you want to know the exact price of 4% 27 - Hydroxyacetophenone, you should consult various cities, consult various merchants, look at its recent trading conditions, and comprehensively consider the above factors to obtain a closer figure. However, it is only a temporary price, which cannot be relied on for a long time. The market conditions are ever-changing, and the price is also volatile.